Different strategies were recommended for patients with AMI based on certain guidelines to reduce mortality and applied in practice routinely. But strict application of the same would bring better outcome in clinical practice. But it was observed adhering to these guidelines are in suboptimal in clinical setting due to variation in temporal and geographical variations. Many of the drugs (E.g. statins, antiplatelet drugs, ACE inhibitors etc.) that could save the life are still being deficit in the prescriptions. Underutilization of drugs is seen more seen females showing gender difference for drug usage and exact cause for this difference is not still known. Hence based on above findings the present study was planned for Clinical Evaluation of Prescription Pattern of Drugs Administered for Myocardial Infarction in Magadh Region Bihar. The present study was planned in Anugrah Narayan Magadh Medical College, Gaya, Bihar, India. In this study 50 cases diagnosed with the Myocardial infarction were enrolled and evaluated. After recording the obtained information in the case record form the data were analyzed further according to demographic profile, social habits, coexisting illness and the drug utilization pattern including routes of administration, category of the drug used in the treatment and fixed-dose combination prescribed. The data generated from the present study it is observed that Anti-platelets, Anti-anginals and Hypo-lipidemic are the mainly drugs prescribed for the Myocardial infraction. The trends in prescribing medication in case of myocardial infarction and the strategies towards its approach has been changes over past few years and it will show further changes in next decade as indicated by the results of this study