Adrenal myelolipoma is a relatively rare benign tumor composed of mature adipose tissues and a variable amount of hematopoietic elements. The incidence of adrenal myelolipoma is 0.08%-0.4%. The male to female ratio is 1:1. We are here reporting a surgically treated case of giant adrenal myelolipoma. A 52 years old man presented in our surgical outpatient clinic with retroperitoneal tumor. Right adrenalectomy was done. The origin of the tumor was suggested to be the right adrenal gland. The weight of the excised tumor was 700gm & size is 14×9.5×7 cm. The histopathological diagnosis was adrenal myelolipoma. The patient had uneventful recovery and was discharged from the hospital. He has been followed up in our outpatient clinic.