Background: The most common cause of endodontic failures has been attributed to incomplete obturation. Bioceramic-based sealers with excellent properties are gaining popularity to fill the gap. But there is a lack of data in comparing these sealers with different obturation techniques. Aim: To assess the apical microleakage and sealer distribution of two sealers using two obturation techniques along the root canal walls. Materials and Methods: 80 single-rooted premolars were randomly divided into two groups for assessing the apical microleakage and sealer distribution using two different bioceramic sealers and two obturation techniques. The samples were checked for vertical dye penetration technique using 2% methylene blue dye and evaluated with a stereomicroscope at 30x magnification to study apical microleakage and sealer distribution.One way ANOVA was carried out to compare between the study groups. Statistical significance was considered at p<0.05. Results: Bioroot RCS with single cone showed lesser apical microleakage when compared with BioRoot RCS with lateral condensation and MTA Fillapex sealer with single cone and MTA Fillapex and lateral condensation. On comparing the sealer distribution between the two bioceramic sealers, it was found that BioRoot RCS with single cone showed better sealer distribution than the other groups. There was a significant difference seen statistically. Conclusions: Among the bioceramic sealers, BioRoot RCS with single cone obturation technique showed the least apical microleakage and the best sealer distribution.