Newborn period is the most critical phase of life as they are prone to various diseases. Survival of the newborn is dependent on availability and accessibility to quality health care system. The present study was planned for Evaluation of Mortality and morbidity pattern and associated factors in the low birth weight babies in sick newborn Care Unit at Darbhanga Medical College and Hospital. The present study was conducted in Department of Pediatrics, Darbhanga Medical College and Hospital, Laheriasarai, Bihar. Total 100 cases of the low birth weight newborns admitted to SNCU in our hospital were enrolled and evaluated. These newborns were divided in different categories based on the different birth weights. The outcome from the present study concludes that Perinatal asphyxia (8%) and infection (12%) are important preventable causes of mortality. Also, the respiratory distress syndrome (4%), Meconium Aspiration Syndrome (24%), neonatal sepsis (12%), neonatal hyperbilirubinemia (14%), and HIES (8%) as the major causes of morbidity. The very Low Birth Weight (43%) and prematurity being the commonest contributors of death.