Comparison of efficacy of Ropivacaine and ropivacaine with clonidine for caudal analgesia in paediatric patients
To compare Ropivacaine (0.25%) and Ropivacaine (0.25%) with Clonidine (1μg/kg) for caudal analgesia in pediatric patients for infra-umbilical surgeries for 1) The duration of postoperative analgesia. 2) The degree of sedation. This study was conducted in 60 children of ASA physical status I and II, weighing less than 20 kg undergoing elective infra-umbilical surgeries. Group A (control): (0.25%) plain Ropivacaine 1ml/kg + Normal saline Group B (study): (0.25%) plain Ropivacaine 1mg/kg + 1μg/kg Clonidine + Normal saline All patients were observed for 2 hours in recovery room. HR, BP, RR were monitored continuously. Postoperative pain was assessed at 30 min,1, 2, 4, 6, 8, 10, 12, 18 and 24 hours after recovery from anesthesia using observer pain score(OPS). Duration of analgesia (time from caudal block to first dose of rescue analgesic or OPS >= 11) was recorded. The time of first rescue analgesia received and total number of doses received in 12 hours were noted in both the groups postoperatively. The duration of analgesia in the post-operative period was prolonged in Group B (10.07±1.15 hours) as compared to Group A (4.85±0.95 hours) OPS score was 11.53±2.47 at 4 hours in Group A and 11.66±3.47 at 10 hours in Group B. There was no significant difference in mean sedation score of both the groups. we conclude and recommend that the addition of clonidine 1μg/kg to Ropivacaine (0.25%) 1ml/kg in caudal epidural, significantly prolongs the duration of analgesia without any adverse effects in pediatric patients undergoing infra-umbilical surgeries.