International Journal of Medical and Health Research

International Journal of Medical and Health Research


International Journal of Medical and Health Research
International Journal of Medical and Health Research
Vol. 7, Issue 12 (2021)

Apnea in preterm neonate following administration of cyclomydril eye drops. Case report


Abdullah Mohammed Kamel, Abdulmajeed Mohammed Alrashoud, Luai Abdulkhaleq Albakkour, Mishary Saud Almalkey, Asma Ibrahim Attieh

Context: Apnea is a prolonged cessation of respiration which is a common presentation in a pediatric emergency department in neonates and premature babies which can be caused by direct depression of CNS control of respiration (hypoglycemia, meningitis, intracranial hemorrhage, seizures), disturbances in oxygen delivery (shock, sepsis, anemia), or ventilation defects (obstruction of the airway, pneumonia, muscle weakness) and can be caused by some drugs. Objective: We report a case of a premature infant presented to the ophthalmology clinic for the regular screening of ROP, and pupils were dilated with Cyclomydril eyedrops. Approximately a few minutes after giving the drops, the baby was unresponsive, apneic, Cyanotic. Patient: The patient came to the ED at 37 weeks’ corrected gestational age when he received Cyclomydril eyedrops to dilate the pupils during his screening for ROP. Approximately a few minutes after giving the drops, the baby was found unresponsive, apnic, cyanotic; the patient was taken by his mother to a pediatric emergency. Upon arrival, the boy was apnic, cyanosed and unresponsive. Conclusions and Outcome: Although very rare, Cyclomydril eye drops have been known to cause apnea, and even hypoxic arrest, in outpatient ophthalmology clinics at routine screening for retinopathy of prematurity. Adverse events such as apneas and bradycardias have been documented to occur up to 24 hours following the instillation of the eye drops. After clinical assessment and investigations, we conclude that these eye drop side effects should be considered a cause of apnea in neonates and premature babies. So, the pediatric ophthalmologists should be equipped to handle this type of emergency, either personally or with ancillary services that are immediately available.
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How to cite this article:
Abdullah Mohammed Kamel, Abdulmajeed Mohammed Alrashoud, Luai Abdulkhaleq Albakkour, Mishary Saud Almalkey, Asma Ibrahim Attieh. Apnea in preterm neonate following administration of cyclomydril eye drops. Case report. International Journal of Medical and Health Research, Volume 7, Issue 12, 2021, Pages 34-36
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