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VOL. 8, ISSUE 2 (2022)
Ampicillin induced anaphylactic shock in a newborn case report
Authors
Saeed Hofan Algarni, Abdullah Mohammed Kamel, Luai Abdulkhaleq Albakkour, Doaa Ali Alhalal, Seham Abdu Alhajoori
Abstract
Context: Anaphylaxis, an allergic reaction that is fast in onset, is rare in the neonatal period due to immaturity of the immunological system. Ampicillin is a broad-spectrum penicillin derivative antibiotic widely used as empiric antimicrobial therapy against Gram-positive and Gram-negative bacteria for severe infections, meningitis, or septicemia in the neonatal period. Objective: We report a case of a 7-day-old girl neonate with ampicillin-induced anaphylaxis. Patient: The patient is a 7-day-old girl neonate who was presented to our emergency department with complaints of fever and continuous diarrhea for one day. The patient was clinically stable; once intravenous ampicillin was administered, the patient suddenly developed mottled skin, cold extremities, apnea, and cyanosis. We observe the sudden clinical deterioration as a drug allergy. Conclusions: Although drug allergies are rare in newborns due to their life-threaten features, close monitoring is essential. Physicians should be aware of the potentially adverse effects of ampicillin in newborns. Physicians should be aware of the potential adverse effects of intravenous antibiotic therapy since rapid assessment and treatment are crucial to reducing morbidity and mortality.
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Pages:16-18
How to cite this article:
Saeed Hofan Algarni, Abdullah Mohammed Kamel, Luai Abdulkhaleq Albakkour, Doaa Ali Alhalal, Seham Abdu Alhajoori "Ampicillin induced anaphylactic shock in a newborn case report ". International Journal of Medical and Health Research, Vol 8, Issue 2, 2022, Pages 16-18
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