ARCHIVES
VOL. 8, ISSUE 2 (2022)
Albuminuria as a risk marker for developing type 2 diabetes in nondiabetic- A study at tertiary care hospital from central India
Authors
Premshanker Singh, Manoj Kumar, Granth Kumar, Vidyasagar
Abstract
This study was conducted amongst rural population of central India at UP University of medical sciences, Saifai, Etawah, India wef Apr 2008 to Apr 2020 (12 years) to determine whether the presence of microalbuminuria and macroalbuminuria is associated with the development of diabetes among nondiabetic rural population. Urine albumin to creatinine ratios (ACRs) were obtained from 1764 rural people aged 20–74 years. Among them 1500 were free of either clinical known diabetes or newly diagnosed diabetes over an 12 years follow-up period, 234 participants developed diabetes. They were defined as cases. Each case was matched by an individual control with same sex and body mass index (BMI) category and age within 2 years. Conditional logistic regression was used to assess the association between albuminuria and diabetes. The baseline level of ACR was significantly higher among cases than among controls. The odds ratios for future diabetes were 2.36 [95% confidence interval (95% CI) 1.01–5.50] and 3.27 (95% CI 1.38–7.77) for middle and upper tertiles, respectively, with adjustment for age, BMI, serum total cholesterol, serum C-reactive protein values and fasting plasma glucose at the baseline. The adjusted odds ratios were 1.90 (95% CI 0.88–4.06) and 2.51 (95% CI 1.08–5.87) for those with microalbuminuria and macroalbuminuria, respectively. The presence of microalbuminuria and macroalbuminuria predicts diabetes independent of other known risk markers of development of type 2 diabetes in Indian people.
Download
Pages:8-12
How to cite this article:
Premshanker Singh, Manoj Kumar, Granth Kumar, Vidyasagar "Albuminuria as a risk marker for developing type 2 diabetes in nondiabetic- A study at tertiary care hospital from central India ". International Journal of Medical and Health Research, Vol 8, Issue 2, 2022, Pages 8-12
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.