Logo
International Journal of
Medical and Health Research
ARCHIVES
VOL. 8, ISSUE 4 (2022)
Assessment of association and correlation between pulse pressure and framingham risk score in type 2 diabetes patients at a Tertiary Care Center in Kishanganj, Bihar-a cross sectional study
Authors
Sourav Chattopadhyay, Sandeep Bharadwaj, Sumit Singh Kaushal, Abhinav Chaudhary, Suman Kumar Singh, Aniket Sinha
Abstract
Purpose of the Study: Pulse pressure (PP) calculated as the difference between systolic blood pressure and diastolic blood pressure has been considered as a preferable predictor of coronary heart disease (CHD) risk than systolic blood pressure (SBP) or diastolic blood pressure (DBP) in older adults. The Framingham Risk Score is a gender-specific algorithm used to estimate the 10-year cardiovascular risk of an individual. Individuals with type 2 diabetes are at greatly increased risk for cardiovascular disease. Although PP is important in predicting mortality among individuals with impaired glucose tolerance, hardly few researches have focused on the predictive value of PP in persons with diabetes mellitus. Methods: An Observational Cross sectional study conducted over a period of 1.5 years at Outpatient department of a tertiary care center located in East Bihar. Type 2 Diabetes Patients were distributed into three groups based on the HbA1C level. (Controlled HbA1c= ≤ 7, Moderately Controlled with HbA1C 7-8, Uncontrolled with HbA1c level ≥8). Sample size of 894 having 298 samples in each group were distributed post sample size calculation using inferential data from a similar study at 95% confidence limit with power of the study at 80% Informed Consent were taken before the Study from each Sample. Ethical Clearance was obtained prior to the study. Pulse pressure and Framingham risk score were calculated and co-related for each group. Data was analysed using SPSS (Statistical Package for the Social Sciences) version 16. All the quantitative parameters such as SBP, DBP, Fasting Blood Sugar (FBS), pulse pressure, Triglycerides, HbA1c and Framingham Risk score were expressed as mean with Standard deviations for all three groups and subjects. Results: Statistically significant association was found using ANOVA and Post-hoc analysis between three different groups and the Pulse pressure (p=0.001, F= 7.7). Although no association was established for Diastolic BP, other parameters SBP, Triglyceride, FBS and FRS showed statistically significant difference amongst the group. Upon Correlation Analysis a positive correlation was obtained between Pulse Pressure and Framingham Risk score in Group II (r =0.136, p =0.019) and Group III (r =0.47, p =< 0.001) of the study. Conclusions: Pulse pressure can be used as an important marker to predict risk for coronary heart disease in type 2 diabetics with uncontrolled HbA1c levels.
Download
Pages:5-7
How to cite this article:
Sourav Chattopadhyay, Sandeep Bharadwaj, Sumit Singh Kaushal, Abhinav Chaudhary, Suman Kumar Singh, Aniket Sinha "Assessment of association and correlation between pulse pressure and framingham risk score in type 2 diabetes patients at a Tertiary Care Center in Kishanganj, Bihar-a cross sectional study". International Journal of Medical and Health Research, Vol 8, Issue 4, 2022, Pages 5-7
Download Author Certificate

Please enter the email address corresponding to this article submission to download your certificate.