Clinico pathological spectrum of acute kidney injury in children admitted to tertiary care centre
Abhijeet Trivedi, Atul Deokar, N C Joshi
Background: Acute kidney injury (AKI) is a frequently encountered clinical entity in children and imposes significant morbidity and mortality. In a resource limited healthcare facilities the treatment of AKI is challenging task for pediatricians and it has been associated with wide range of adverse outcomes. The main aim of the present study was to evaluate the clinicopathological profile and outcome of AKI. Methods: This prospective study was carried out on 30 children admitted to pediatric medical wards over a period of 2.5 years. Children aged 1day to 12 years diagnosed with AKI irrespective of the underlying cause were included. Detailed medical information of the children was recorded and the baseline investigations were noted. Clinical and etiological profile of were also obtained. Results: In this study, the incidence of AKI was higher among the children with age group between 1 month- 5 years (63.3%). The major cause of AKI was due to acute tubular necrosis (ATN) encompassing 80%. Further, 33.3% of children were managed by dialysis and most of them underwent peritoneal dialysis. Mortality was observed in 7 out of 30 children (23.3%) and the main risk factor was dialysis, hypertension and dehydration. Conclusion: The main cause of AKI in the present study was acute tubular necrosis. Dialysis, hypertension and dehydration are the main predictors of mortality.
Abhijeet Trivedi, Atul Deokar, N C Joshi. Clinico pathological spectrum of acute kidney injury in children admitted to tertiary care centre. International Journal of Medical and Health Research, Volume 8, Issue 5, 2022, Pages 1-4