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VOL. 9, ISSUE 5 (2023)
Inflammatory bowel disease and metabolomics- Are they connected?
Authors
D Gashkova, E Ivanova, D Notev
Abstract
Crohn’s disease and
ulcerative colitis are the two major diseases in the group of inflammatory
bowel diseases of the GI tract. There is increasing incidence of both UC and
Crohn’s disease. Pathogenesis is not completely defined, the current theory
being a complex interaction between genetics, the environment and the
microbiota in a susceptible individual. Diagnosis requires clinical, laboratory,
endoscopic, radiologic and histologic studies and in 15% of patients are it is
not possible to differentiate between the two – so called “IBD-unclassified”.
Metabolomics measures metabolites in a biological sample (feces, serum, urine,
tissue and air) thereby having the potential to clarify disease pathogenesis
and find new biomarkers, which will then aid in diagnosis, guide therapy and
give prognosis.
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Pages:31-35
How to cite this article:
D Gashkova, E Ivanova, D Notev "Inflammatory bowel disease and metabolomics- Are they connected?". International Journal of Medical and Health Research, Vol 9, Issue 5, 2023, Pages 31-35
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