Acute variceal bleeding is a major cause for
mortality in patients with liver cirrhosis with mortality rate around 15%.
Resuscitaion with blood tranfusions and volume replacement is a key step in the
management of these patients, combined with administration of vasoactive drugs
and endoscopic variceal band ligation. Tansjugular intrahepatic
portosystemic shunt (TIPS) with appropriate indications is an option for some
patients with treatment failure, but also has limitations related to the prognosis of the individual patient. Bridge therapy with balloon
tamponade or specially designed coated esophageal stents can be used for unstable
patients awaiting
definitive treatment. Early TIPS should be the first choice in
patients at high risk of treatment failure (Child-Pugh B with active bleeding
or Child-Pugh C < 14).
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