Background: Hypertension (HTN) is a common health problem of the cardiovascular system that known as "silent killer", It is one of the major avoidable risk factors for noncommunicable diseases that contributes to early death and disability.

Purpose: to examine the impact of different BMI on HGS, HGE, and body function in hypertensive patients.

Materials and Methods: One Hundred Twenty subjects of both sex participated in this study, their age was ranging between 40-69 years, they were randomly allocated into 2 groups equal Normal group (Group A) involved 60 healthy subjects without HTN and hypertension group (Group B) involved 60 patients with HTN. Each group divided into 3 equal sub-groups (normal weight BMI from  18.5 to <25 kg/m², overweight BMI from  25 to <30 kg/m², as well as Obese BMI  30 kg/m²), each BMI sub-group included 20 subjects. BMI was measured by Digital Platform Weighing Scale, Hypertension was assessed by Mercury Sphygmomanometer, Hand Grip strength along with Hand Grip Endurance were measured by Digital Hand Dynamometer of the dominant hand and body function by using the SF-36 questionnaire.

Results: Post-hoc test revealed that handgrip strength was more in overweight BMI subgroup in both normal and hypertension groups with a mean of 31.0 ±6.71 and 29.4 ±6.75 kg respectively, also endurance time was more in overweight BMI subgroup in both normal and hypertension groups with a mean of 134.8 ±21.5 and 127.1 ±37.5 s. No significant correlation between BMI with HGS, HGE, and endurance time (P>0.05) in both normal and hypertension groups, but there were significant differences (P<0.05) in mean values of HGS among normal group and hypertension group in obese BMI subgroup, moreover there were significant differences (P<0.05) in mean values of total score SF-36 questionnaire between normal group and hypertension group for normal BMI (P=0.002) and obese BMI (P=0.044) subgroups. But, there wasn’t statistical significant difference (P>0.05) in mean values of total score SF-36 questionnaire between both groups for overweight BMI subgroup (P=0.129).

Conclusion: There was significantly negative moderate relation between BMI and body function. However, there were no significantly relations among BMI with HGS and HGE.