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VOL. 11, ISSUE 2 (2025)
Histopathology of pancreatic cancer: A comprehensive review
Authors
Eyika A Yetunde, Agnes E Inyang, Biya Cephas, Hadizat I Ogah, Solomon M Gamde
Abstract
Pancreatic cancer is one of the most difficult malignancies to diagnose because it early stages are often asymptomatic
and the overlapping features with other forms
of pancreatic disorders. In regions where healthcare resources are constrained, the true burden is
underestimated, as many cases either go undiagnosed or are misclassified as other diseases with similar
symptoms. Histopathology investigation plays a
crucial role in establishing a definitive diagnosis. Common features such as
poorly differentiated glandular structures, significant desmoplasia, and the
unique tumor micro-environment defined by hypovascularity
highlight the aggressive nature of pancreatic adenocarcinoma. Cytological techniques, particularly endoscopic ultrasound-guided
fine-needle aspiration have revolutionized the diagnostic landscape, enabling a broader scope
of pancreatic neoplasms. The integration of morphological assessments with
background features such as necrosis and mucin content enhances diagnostic
accuracy and improved patient outcomes.
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Pages:16-25
How to cite this article:
Eyika A Yetunde, Agnes E Inyang, Biya Cephas, Hadizat I Ogah, Solomon M Gamde "Histopathology of pancreatic cancer: A comprehensive review". International Journal of Medical and Health Research, Vol 11, Issue 2, 2025, Pages 16-25
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