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VOL. 11, ISSUE 3 (2025)
Phytochemical analysis and antimicrobial potential of cissus quadrangularis extracts
Authors
Amrinder Kaur, Sushma, Seema Rani
Abstract
Cissus quadrangularis,
a succulent plant used in traditional medicine, was studied for its antimicrobial
and phytochemical properties. Extracts were prepared using various solvents
(methanol, ethanol, chloroform, ethyl acetate) and tested against bacterial and
fungal strains using agar well diffusion. The phytochemical screening revealed
the presence of steroids, flavonoids, tannins, and phenolics. Antimicrobial
assays showed notable activity against Staphylococcus aureus, E. coli,
and Candida albicans, especially in methanol and ethyl acetate extracts.
These findings support the traditional use of C. quadrangularis and its
potential as a source of antimicrobial agents. Cissus quadrangularis, a
medicinal plant traditionally used in Ayurvedic and folk medicine, was
investigated for its phytochemical profile and antimicrobial efficacy. The
study aimed to evaluate the antibacterial and antifungal activities of various
solvent extracts (methanol, ethanol, ethyl acetate, and chloroform) of the
plant stem and identify key bioactive compounds responsible for these
activities. Soxhlet extraction methods were employed for extract preparation,
followed by phytochemical screening using standard protocols. The presence of
triterpenoids, flavonoids, steroids, phenolics, and tannins was confirmed
across all extracts. Antimicrobial activity was assessed via the agar well
diffusion method against a panel of bacterial and fungal pathogens including Escherichia
coli, Staphylococcus aureus, Enterobacter aerogenes, Leuconostoc
mesenteroides, and Candida albicans. Among the extracts, methanol
and ethyl acetate demonstrated the highest inhibitory effects, particularly
against gram-positive bacteria and fungal strains. The observed activity
underscores the potential of C. quadrangularis as a source of natural
antimicrobial agents. The results support the traditional use of the plant in
treating infections and provide a scientific basis for its pharmacological
applications in antimicrobial drug development.
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Pages:62-65
How to cite this article:
Amrinder Kaur, Sushma, Seema Rani "Phytochemical analysis and antimicrobial potential of cissus quadrangularis extracts". International Journal of Medical and Health Research, Vol 11, Issue 3, 2025, Pages 62-65
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