This study was conducted to understand the role of androgens (testosterone, dihydrotestosterone, and dehydroepiandrosterone) in addition to estrogen and their effect on the growth of the male reproductive organs and the relationship of these hormones, in the event of their decrease or increase, to deformities of the male reproductive system organs during fetal development or after birth. The study included 45 male children aged from 6 months to 12 years from Mosul city. They were divided into three groups. The first group included 15 children who did not suffer from this type of deformity and had no family history of this defect. They were used as a control group. The other group included 15 children who suffered from cryptorchidism and 15 children who suffered from hypospadias.