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VOL. 11, ISSUE 4 (2025)
Evaluetion of serum levels of cardiac biomarkers troponin I and troponin T in women using injectable, Implanon, and oral contraceptives among women
Authors
Mohammed Umar, Solomon D Mariam, Okoli A Caroline
Abstract
Hormonal contraceptives are widely used
methods for preventing pregnancy in women. Their use has been associated with
changes in cardiac biomarkers, which may lead to congestive heart failure, deep
vein thrombosis, arteriosclerosis, and stroke and major causes of premature
death. This study aimed to evaluate the serum levels of cardiac biomarkers
Troponin I and Troponin T in women using injectable, Implanon, and oral
contraceptives. A comparative cross-sectional case-control study was conducted
on 225 hormonal contraceptive users and 225 control subjects. Serum levels of
Troponin I and T were analyzed using a chemiluminescence method. Data were
analyzed using SPSS version 23. The significance level was set at p<0.05.
T-tests were used to compare the means between two groups, and one-way ANOVA. Results
showed that Troponin I levels were significantly higher (p = 0.041) in women
using contraceptives compared to controls. However, Troponin T levels were not
significantly different (p = 0.685). Hormonal contraceptive effects are
influenced by age, type, and duration of use. Risk assessment through cardiac
biomarker assays is recommended to identify the safest contraceptive option.
Male partners are also encouraged to consider vasectomy to reduce women’s
exposure to potential adverse effects.
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Pages:28-29
How to cite this article:
Mohammed Umar, Solomon D Mariam, Okoli A Caroline "Evaluetion of serum levels of cardiac biomarkers troponin I and troponin T in women using injectable, Implanon, and oral contraceptives among women". International Journal of Medical and Health Research, Vol 11, Issue 4, 2025, Pages 28-29
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