Background: Ulcerative colitis is a distinct gastrointestinal condition that can severely impact quality of life. While conventional treatments may involve surgery or immunosuppressants, integrative approaches like Yoga Prana Vidya (YPV) are gaining recognition for their holistic benefits.

Objective: To document the application and outcomes of YPV healing protocols in a 33-year-old married woman diagnosed with rectal ulcerative colitis, highlighting the therapeutic effects.

Case Presentation: The patient reported persistent abdominal pain, fatigue, rectal bleeding, and altered bowel habits. Clinical investigations confirmed ulcerative colitis localized to the rectum. Under guided supervision, she underwent regular YPV healing sessions conducted by two expert YPV healers over 3 months with time gaps, which included energy cleansing and energising by healer, pranic breathing, psychological healing through forgiveness practices, and dietary regulation.

Results: The YPV intervention yielded marked symptomatic relief—abdominal discomfort subsided, bowel movements normalized, bleeding ceased, and her energy levels improved significantly. Follow-up assessments demonstrated physiological progress without the need for surgical intervention. No adverse effects were noted during the healing process.