Introduction: Oil pulling, an ancient Ayurvedic oral hygiene practice, has garnered modern interest for its potential systemic and local health benefits. Due to its lauric acid content, pure coconut oil is recognized for its potent antimicrobial properties.

Aim: This study evaluated the immediate impact of oil pulling using pure coconut oil on the salivary count of Streptococcus mutans (S. mutans), comparing its effectiveness against sesame oil and a saline rinse.

Materials and Methods: A randomized controlled concurrent parallel-triple blinded clinical trial was conducted. Thirty participants (students aged 20-23 years) were randomly divided into Group A (coconut oil), Group B (sesame oil), and Group C (saline). Unstimulated saliva was collected immediately before and after the 10–15 minute swishing procedure to analyze S. mutans Colony Forming Units (CFU) per ml of saliva. Data analysis was performed using appropriate statistical tests, with a significance level set at (P<0.05).