Polycystic Ovary Disease (PCOD), also known as Polycystic Ovary Syndrome (PCOS), is a prevalent endocrine and metabolic disorder affecting women of reproductive age, with increasing incidence among adolescents and young adults. The present study aimed to assess the prevalence, awareness, symptomatology, lifestyle factors, and management practices associated with PCOD among students of Isabella Thoburn College, Lucknow. A cross-sectional survey was conducted using a structured questionnaire administered through an online platform. A total of 67 female students participated in the study. The findings revealed a high prevalence of PCOD-related symptoms, with 79.1% of respondents reporting a confirmed medical diagnosis. Most participants belonged to the age group of 18–21 years, indicating that late adolescence and early adulthood represent a critical period for the onset and diagnosis of the condition. Menstrual irregularities were highly prevalent, with 72.7% of respondents reporting irregular cycles, along with associated symptoms such as painful menstruation (74.6%), hair loss (71.6%), mood disturbances (71.6%), and weight gain (59.7%). Lifestyle assessment indicated that a significant proportion of participants followed unhealthy dietary patterns, experienced inadequate sleep, and engaged in low or irregular physical activity, all of which are known to exacerbate PCOD symptoms.