The study to assess the role of ultrasound in estimation of focal hepatic lesions was planned in Patna Medical College and Hospital. Total 50 patients in age group of 25-65 years were enrolled in to the study. Liver was scanned in various planes. Various ultrasonographic features of focal liver lesions were observed. The maximum ultrasound diagnoses were confirmed by the CT scan. The main aim of the present study is to assess the role of ultrasound in estimation of focal hepatic lesions. The primary function of investigating a focal liver lesion is to characterise it with confidence as either needing no or only routine follow-up, or needing further, more rigorous exploration (including biopsy). The exclusion of malignancy is paramount, and most benign lesions can be characterised on non-invasive imaging grounds alone. Conventional ultrasonography is often used as the first line imaging investigation. High degree of sensitivity and specificity of ultrasonographic diagnosis in the present study confirms the value of ultrasonographic evaluation of focal liver lesions and suggests that it can be effectively used in the routine diagnostic work.